abstract：:The utility of postmortem microbiology has continuously been a topic of controversy. The present study describes a case of fatal sepsis in a patient with systemic lupus erythematosus. Postmortem culture and genotyping analyses allowed us to identify Klebsiella pneumoniae as the cause of sepsis, revealing the inadequat...

journal_title：International journal of legal medicine

authors： D'Ovidio C,Pompilio A,Crocetta V,Gherardi G,Carnevale A,Di Bonaventura G

更新日期：2015-09-01 00:00:00

abstract：:Growth arrest-specific 6 (Gas6) is widely expressed in leukocytes, platelets, endothelial cells, and monocytes. It regulates various processes including granulocyte adhesion to the endothelium, cell migration, thrombus stabilization, and cytokine release. In humans, increased plasma Gas6 levels have been described in ...

journal_title：International journal of legal medicine

authors： Palmiere C,Augsburger M

更新日期：2015-09-01 00:00:00

abstract：:The assessment of age at death for identification purposes is a frequent and tough challenge for forensic pathologists and anthropologists. Too frequently, visual assessment of age is performed on well-preserved corpses, a method considered subjective and full of pitfalls, but whose level of inadequacy no one has yet ...

journal_title：International journal of legal medicine

authors： Amadasi A,Merusi N,Cattaneo C

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:The response to traumatic brain injury (TBI) is complex and induces various biological pathways in all brain regions that contribute to bad outcomes. The cerebellar hypoxia after a frontal cortex injury may potentiate the pathophysiological impacts of TBI. Therefore, a gene expression analysis was conducted to ...

journal_title：International journal of legal medicine

authors： Schober K,Ondruschka B,Dreßler J,Abend M

更新日期：2015-07-01 00:00:00

abstract：:One of the most common conditions during fetal development is anencephaly, which often involves many identification difficulties in the context of physical anthropology, as it causes severe skull challenges. In this paper, we describe the alterations found in the skulls of two perinatal individuals with anencephaly fr...

journal_title：International journal of legal medicine

authors： Irurita J,Alemán I,Viciano J,López-Lázaro S,Botella MC

更新日期：2015-07-01 00:00:00

abstract：:The genetic polymorphisms of 15 autosomal short tandem repeat (STR) loci included in the AmpFISTR Sinofiler™ kit were evaluated in 547 healthy unrelated Han individuals from Gansu, China. All of the loci reached the Hardy-Weinberg equilibrium after the Bonferroni correction (p > 0.0033). These loci were examined to de...

journal_title：International journal of legal medicine

authors： Sun M,Zhang X,Wu D,Shen Q,Wu Y

更新日期：2015-07-01 00:00:00

abstract：:Gabapentin (GBP) (Neurontin®, Horizant®, Gralise®) is a widely prescribed medication used primarily for the treatment of epilepsy and neuropathic pain. GBP has a favorable adverse effect profile in therapeutic dosing with the most common reported effects being dizziness, fatigue, drowsiness, weight gain, and periphera...

journal_title：International journal of legal medicine

authors： Cantrell FL,Mena O,Gary RD,McIntyre IM

更新日期：2015-07-01 00:00:00

abstract：:Postmortem MRI (PMMR) examinations are seldom performed in legal medicine due to long examination times, unfamiliarity with the technique, and high costs. Furthermore, it is difficult to obtain access to an MRI device used for patients in clinical settings to image an entire human body. An alternative is available: ex...

journal_title：International journal of legal medicine

authors： Bruguier C,Egger C,Vallée JP,Grimm J,Boulanger X,Jackowski C,Mangin P,Grabherr S

更新日期：2015-05-01 00:00:00

abstract：:Volatile substances are used widespread, especially among young people, as a cheap and easily accessible drug. Tetrachloroethylene is one of the solvents exerting effects on the central nervous system with experiences of disinhibition and euphoria. The case presented is that of a 27-year-old female, found dead by her ...

journal_title：International journal of legal medicine

authors： Amadasi A,Mastroluca L,Marasciuolo L,Caligara M,Sironi L,Gentile G,Zoja R

更新日期：2015-05-01 00:00:00

abstract：:Reports on penetrating ballistic head injuries in the literature are dominated by case studies of suicides; the penetrating ammunition usually being .22 rimfire or shotgun. The dominating cause of injuries in modern warfare is fragmentation and hence, this is the primary threat that military helmets protect the brain ...

journal_title：International journal of legal medicine

authors： Carr D,Lindstrom AC,Jareborg A,Champion S,Waddell N,Miller D,Teagle M,Horsfall I,Kieser J

更新日期：2015-05-01 00:00:00

abstract：:2-Amino-5-chloropyridine (ACP) is a degradation product of zopiclone (ZOP) and its two main metabolites N-desmethylzopiclone (NDZOP) and zopiclone N-oxide (ZOPNO). ACP may be formed when specimens are stored. ZOP instability in blood makes interpretation of concentrations difficult especially in cases of prolonged sam...

journal_title：International journal of legal medicine

authors： Nilsson GH,Kugelberg FC,Ahlner J,Kronstrand R

更新日期：2015-03-01 00:00:00

abstract：:Severe cold stress has been shown to cause changes in the expression and secretion of thrombomodulin (TM), an endothelial protein regulating haemostasis and inflammation. To further evaluate TM as a cold stress indicator, relative TM mRNA and TM protein levels in the myocardium and the concentrations of TM in serum an...

journal_title：International journal of legal medicine

authors： Pakanen L,Kaija H,Kortelainen ML,Särkioja T,Porvari K

更新日期：2015-03-01 00:00:00

abstract：:Multiple tooth development staging techniques were reported based on arbitrarily set borderlines between succeeding stages. Anatomic tooth features or predictions of future tooth part dimensions were described to identify the thresholds between the established stages. The need to predict mature tooth dimensions, while...

journal_title：International journal of legal medicine

authors： Altalie S,Thevissen P,Willems G

更新日期：2015-01-01 00:00:00

abstract：:In this study, we assessed 30 insertion-deletion polymorphisms (Indels) (Investigator DIPplex® kit) in four Chinese populations (n = 952) and evaluated their usefulness in forensic genetic applications. After the Bonferroni correction at a 95 % significance level (p = 0.0017), there were no deviations from the Hardy-W...

journal_title：International journal of legal medicine

authors： Shi M,Liu Y,Bai R,Jiang L,Lv X,Ma S

更新日期：2015-01-01 00:00:00

abstract：:Cocaine and alcohol toxicity is well known, especially when simultaneously abused. These drugs perform both acute and chronic harmfulness, with significant cardiac events such as ventricular arrhythmias, tachycardia, systemic hypertension, acute myocardial infarction, ventricular hypertrophy, and acute coronary syndro...

journal_title：International journal of legal medicine

authors： Cittadini F,De Giovanni N,Alcalde M,Partemi S,Carbone A,Campuzano O,Brugada R,Oliva A

更新日期：2015-01-01 00:00:00

abstract：:For a long time, it has been thought that fresh and frozen tissues are the only possible source of biological material useful to extract nucleic acids suitable for downstream molecular analysis. Recently, for forensic purpose such as personal identification, also fixed tissues have been used to recover DNA molecules, ...

journal_title：International journal of legal medicine

authors： Muciaccia B,Vico C,Aromatario M,Fazi F,Cecchi R

更新日期：2015-01-01 00:00:00

abstract：:Forensic age estimation of living individuals has become increasingly important in forensic practice with the constant increase of migration movements to developed countries. The method of Greulich and Pyle is one of the most frequently used methods for age determination. The aim of our study was to verify the reliabi...

journal_title：International journal of legal medicine

authors： Zabet D,Rérolle C,Pucheux J,Telmon N,Saint-Martin P

更新日期：2015-01-01 00:00:00

abstract：:When a Y-chromosomal and a (partial) autosomal DNA profile are obtained from one crime sample, and both profiles match the suspect's profiles, we would like to know the combined evidential value. To calculate the likelihood ratio of observing the autosomal and Y-chromosomal DNA profiles combined, we need to know the c...

journal_title：International journal of legal medicine

authors： de Zoete J,Sjerps M,Meester R,Cator E

更新日期：2014-11-01 00:00:00

abstract：:The purpose of this study is to evaluate allelic association and linkage of 18 adjacent syntenic short tandem repeat (STR) pairs form out of 30 markers located on 12 different autosomes. Linkage disequilibrium was tested by using the unknown gametic phase genotypes and phased haplotypes from 290 unrelated individuals ...

journal_title：International journal of legal medicine

authors： Wu W,Hao H,Liu Q,Han X,Wu Y,Cheng J,Lu D

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The annual number of detainees held in police custody in France is approximately 700,000. Medical data regarding arrestees are scarce across countries. We present the medical characteristics of detainees kept in police custody, including addictive behaviours and high-risk medical situations. M...

journal_title：International journal of legal medicine

authors： Chariot P,Beaufrère A,Denis C,Dang C,Vincent R,Boraud C

更新日期：2014-09-01 00:00:00

abstract：:Methadone plays an increasing role in drug-related deaths in Hamburg. To find out whether intravenous application of methadone plays a relevant role in methadone-related deaths, body fluids of all methadone-positive cases (n=130) and three buprenorphine-positive cases where a urine sample was available (n=58+3) were i...

journal_title：International journal of legal medicine

authors： Iwersen-Bergmann S,Jungen H,Andresen-Streichert H,Müller A,Elakkary S,Püschel K,Heinemann A

更新日期：2014-09-01 00:00:00

abstract：:Species identification from hair has been performed in the past by several techniques, such as scanning electron microscopy and polymerase chain reaction. Despite the great promise of mass spectrometry herein, the repetitive glycine stretches and the evolutionary conserved sequences of keratins make the results from c...

journal_title：International journal of legal medicine

authors： Van Steendam K,De Wulf O,Dhaenens M,Deforce D

更新日期：2014-09-01 00:00:00

abstract：:Postmortem ethanol formation is a well-known problem in forensic toxicology. The aim of this study was to interpret findings of ethanol in blood, in a large collection of forensic autopsy cases, by use of the nonoxidative ethanol metabolites, ethyl glucuronide (EtG), and ethyl sulfate (EtS). In this study, according t...

journal_title：International journal of legal medicine

authors： Krabseth H,Mørland J,Høiseth G

更新日期：2014-09-01 00:00:00

abstract：:The ability to estimate stature from various parts of the body is essential in medicolegal investigations, particularly in cases in which human remains have been dismembered or mutilated. Therefore, the aim of this study was to generate linear regression models for predicting stature on the basis of sternum length in ...

journal_title：International journal of legal medicine

authors： Macaluso PJ Jr,Lucena J

更新日期：2014-09-01 00:00:00

abstract：:Brazilian population derives from Native Amerindians, Europeans, and Africans. Southeastern Brazil is the most populous region of the country. The present study intended to characterize the maternal genetic ancestry of 290 individuals from southeastern (Brazil) population. Thus, we made the sequencing of the three hyp...

journal_title：International journal of legal medicine

authors： Fridman C,Gonzalez RS,Pereira AC,Cardena MM

更新日期：2014-07-01 00:00:00

abstract：:DNA-based prediction for externally visible characteristics such as eye color is already a useful tool in forensic criminal investigations. The IrisPlex system, consisting of six single nucleotide polymorphisms (SNPs) and a prediction model, was developed based on individuals from several European populations. Other r...

journal_title：International journal of legal medicine

authors： Yun L,Gu Y,Rajeevan H,Kidd KK

更新日期：2014-05-01 00:00:00

abstract：:To increase the reliability of forensic age estimations in living adolescents and young adults where there is no legitimation for X-ray examinations, it would be desirable to establish radiation-free imaging methods. In the present study, the ossification stage of the distal femoral epiphysis was determined retrospect...

journal_title：International journal of legal medicine

authors： Krämer JA,Schmidt S,Jürgens KU,Lentschig M,Schmeling A,Vieth V

更新日期：2014-05-01 00:00:00

abstract：:Expert witness opinion based on the comparison of images has been accepted by UK courts as admissible evidence in relation to issues of identity. Within images of the hand are a multiplicity of anatomical features of different aetiology, incidence and distribution patterns and this includes melanocytic nevi, referred ...

journal_title：International journal of legal medicine

authors： Black S,MacDonald-McMillan B,Mallett X,Rynn C,Jackson G

更新日期：2014-05-01 00:00:00

abstract：:Forensic identification comprises legal, social, ethical, and religious aspects where age detection is an important factor. When the case is a fetus or infant, recording various measurements of the body, head, and teeth is essential. The aim of this research is to evaluate the effects of different tooth and body measu...

journal_title：International journal of legal medicine

authors： Dagalp R,Aka PS,Canturk N,Kedici I

更新日期：2014-05-01 00:00:00

abstract：:The estimation of the minimum postmortem interval can be implemented by age estimation of corpse-associated primary colonizers such as the blow flies (Diptera: Calliphoridae). In cases where pupae represent the oldest stages found on a body, their age must be added to the duration of prepupal development to estimate t...

journal_title：International journal of legal medicine

authors： Boehme P,Spahn P,Amendt J,Zehner R

更新日期：2014-05-01 00:00:00

abstract：:Allele frequency distributions for 15 tetrameric short tandem repeat (STR) loci were determined using the AmpFlSTR® Identifiler Plus™ PCR amplification kit. There was little evidence of departures from Hardy-Weinberg equilibrium or association of alleles of different loci in the population samples. The probability of ...

journal_title：International journal of legal medicine

authors： Lucassen A,Ehlers K,Grobler PJ,Shezi AL

更新日期：2014-03-01 00:00:00

abstract：:A block of an injury instrument will be left in wounds sometimes, and the suspect instrument can be discriminated by comparison with the block that was left through elemental analysis. In this study, three brands (Shibazi, Zhangxiaoquan, Qiaoxifu) of kitchen knives with forged, chop, and slice application series were ...

journal_title：International journal of legal medicine

authors： Bai RF,Ma SH,Zhang HD,Chang L,Zhang Z,Liu L,Zhang FQ,Guo ZM,Shi MS

更新日期：2014-03-01 00:00:00

abstract：:In forensic pathology routine, fatal cases of contrast agent exposure can be occasionally encountered. In such situations, beyond the difficulties inherent in establishing the cause of death due to nonspecific or absent autopsy and histology findings as well as limited laboratory investigations, pathologists may face ...

journal_title：International journal of legal medicine

authors： Palmiere C,Comment L,Mangin P

更新日期：2014-01-01 00:00:00

abstract：:Kinship relation and, in particular, paternity probability estimation using a Bayesian approach require the input of a priori probabilities of different hypotheses. In practical case work, a priori probabilities or priors, for short, must often be estimated using only common sense and symmetry arguments because in mos...

journal_title：International journal of legal medicine

authors： Hubig M,Sanft J,Muggenthaler H,Mall G

更新日期：2013-11-01 00:00:00

abstract：:The Ion AmpliSeq™ HID single nucleotide polymorphism (SNP) panel, a primer pool of 103 autosomal SNPs and 33 Y-SNPs, was evaluated using the Ion 314™ Chip on the Ion PGM™ Sequencer with four DNA samples. The study focused on the sequencing of DNA at three different initial target quantities, related interpretation iss...

journal_title：International journal of legal medicine

authors： Seo SB,King JL,Warshauer DH,Davis CP,Ge J,Budowle B

更新日期：2013-11-01 00:00:00

abstract：:As a contribution to the geographic coverage of EMPOP, currently the best available forensic mitochondrial DNA (mtDNA) database, a total of 299 Swedish individuals were analysed by sequencing of the first and second hypervariable regions of the mtDNA genome. In this sample set, a total of 179 different haplotypes were...

journal_title：International journal of legal medicine

authors： Lembring M,van Oven M,Montelius M,Allen M

更新日期：2013-11-01 00:00:00

abstract：:Bone marrow (BM) analysis is of forensic interest for postmortem toxicological investigations where blood samples are unavailable or unusable. Due to the lack of studies, it remains difficult to interpret concentrations of xenobiotics measured in this matrix. Based on a statistical approach published previously to int...

journal_title：International journal of legal medicine

authors： Bévalot F,Gustin MP,Cartiser N,Gaillard Y,Le Meur C,Fanton L,Guitton J,Malicier D

更新日期：2013-09-01 00:00:00

abstract：:CT scan coupled with autopsy is the gold standard for the forensic investigation of fatal road traffic accidents. The objective of the present paper is to demonstrate that from this, it is possible to reconstruct elements of an accident with minimal human and material resources using basic knowledge of three-dimension...

journal_title：International journal of legal medicine

authors： Benali L,Gromb S,Bou C

更新日期：2013-09-01 00:00:00

abstract：:Finding spermatozoa is of the utmost importance in judicial cases involving both the living and the dead; however, most of literature actually deals with inner genitalia and does not take into consideration the chance of external deposition of semen on skin, which is not rare. In addition, the most advanced microscopi...

journal_title：International journal of legal medicine

authors： Gibelli D,Mazzarelli D,Rizzi A,Kustermann A,Cattaneo C

更新日期：2013-09-01 00:00:00

abstract：:For over a century, law enforcement agencies, forensic laboratories, and penal courts worldwide have used fingerprint impressions as reliable and conclusive evidence to identify perpetrators of criminal activity. Although fingerprint identification has been repeatedly proven as one of the most robust and definite fore...

journal_title：International journal of legal medicine

authors： De Alcaraz-Fossoul J,Mestres Patris C,Balaciart Muntaner A,Barrot Feixat C,Gené Badia M

更新日期：2013-07-01 00:00:00